NOT KNOWN FACTUAL STATEMENTS ABOUT MIF

Not known Factual Statements About mif

Not known Factual Statements About mif

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MIF also has the opportunity to communicate with embryonic stem cells (ESC). Wang et al. (2012) lose gentle on this phenomenon by injecting undifferentiated ESC in to the spinal cord of wild-kind mice and MIF knockout mice. Hind limb purpose was calculated applying the Basso Mouse Scale (BMS), which was to begin with ordinary for equally teams of mice.

identify your collection: identify have to be less than 100 people pick a group: not able to load your collection as a result of an mistake

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just after 10 days, the BMS rating swiftly lowered to zero (indicating paralysis) within the WT mice. However, the BMS score from the MIF knockout mice a little bit declined, with only one mouse currently being paralyzed by day 17 [fourteen]. This analyze indicates that MIF interferes with and has an effect on the pluripotency of ESCs by endorsing embryonic stem cell to proliferation.

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